Event by Novo Nordisk Foundation Science Cluster

    Conference: PTMS in Cell Signaling

    Post-translational modifications(PTMs) in cell signaling have evolved as the eukaryotic cell’s most important regulatory mechanism to regulate intracellular protein networks in response to external or internal cues. Site-specific modification of proteins by PTMs such as phosphorylation, ubiquitylation, and acetylation are involved in virtually all signaling pathways that orchestrate fundamental cellular processes including cell cycle progression, apoptosis, the DNA damage response, autophagy, and metabolism. Deregulation of proteins involved in these important cellular responses can often lead to disease, and the enzymes catalyzing addition or removal of PTMs have therefore emerged as prominent therapeutic targets. The meeting will focus on the cellular regulation of these fundamental processes by bringing together world leading researchers in the area of PTM functions in different cell signaling networks.

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    02-06 December 2012


    Andre Nussenzweig
    Angus Lamond
    Brenda Schulman
    Doug Lauffenburger
    Eric Verdin
    Forest White
    Gerald Hart
    Henrik Semb
    Ivan Dikic
    Jiri Lukas
    Matthias Mann
    Michael Yaffe
    Philippe Bastiaens
    Steve Jackson
    Søren Brunak
    Tim Hunt

    Conference topics

    Conference topics

    DNA damage signaling
    Signaling systems and networks
    Cell cycle
    Metabolism and aging
    Epigenetics and cancer signaling
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