Event by Novo Nordisk Foundation Science Cluster

    Lecture: Discovery of Novel Antibiotics

    The Copenhagen Bioscience Lectures are a series of open lectures for all researchers and other interested in and around the Copenhagen area. Every 4 weeks, on a Thursday evening, you are invited for lectures on themes with a general interest for the Novo Nordisk Foundation Research Centers and bioscience researchers in general. Often there will be a cross-disciplinary focus. We are happy to announce Tilmann Weber, Professor at NNF Center for Biosustainability, Technical University of Denmark, and Lone Gram, Professor at the Department for Biotechnology and Biomedicine, Technical University of Denmark.

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    10 January 2019


    Tilmann Weber Professor at Novo Nordisk Foundation Center for Biosustainability
    Lone Gram Professor at the Department for Biotechnology and Biomedicine, Technical University of Denmark

    Integration of Informatics and Metabolic Engineering for the discovery of Novel Antibiotics

    Tilmann Weber: The DNA treasure hunt – how genomics data helps us to find novel antibioticsMost antibiotics that we use to treat infectious diseases are, or are derived from microorganisms.
    While in the past, most of these compounds were identified in classical screening campaigns, nowadays omics technologies play a crucial role in the antimicrobial drug discovery process. Genome analyses of antibiotics producing microorganisms indicate that their genetic potential to synthesize secondary metabolites goes far beyond the number of molecules observed in traditional screenings. Thus, mining the genomic data for natural products biosynthetic pathways has emerged as an important technology complementing the chemical approaches. In this talk, I will introduce our strategies and bioinformatics tools to mine such data and use it as a basis for understanding and engineering the biosynthesis of the chemically very complicated molecules.

    Lone Gram: Secondary metabolites from marine bacteria: use in biotechnology and role in ecology
    Mankind is in dire need for novel antibiotics. Most of our current antibiotics are derived from terrestrial (soil) microorganisms, in particular Streptomyces and filamentous fungi. Bioprospecting hitherto un-explored ecosystems and organisms is one of several strategies to find novel compounds. In this talk, the potential of marine bacteria as source of novel antibiotics is discussed with special emphasis on ecology-based approaches to unlocking the large potential of Gram-negative bacteria.


    3:45 pm Welcome and registration (coffee/tea, water available)
    4:00 pm Start of the lecture
    5:30 pm Networking with a drink and a snack
    6:30 pm Thank you for a splendid end of day!
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    I would like to know about upcoming Copenhagen Bioscience Lectures – where can I find information?

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    What are my transport/parking options getting to the event?

    The organiser offers to pay for a taxi on the following conditions: it has to be transport from either Panum/Mærsk Tower or DTU building 220, if you are at least 3 people in a taxi. This is how it works: you arrange yourself for a taxi from Blegdamsvej or from Kemitorvet, find at least 2 other people to take the taxi with, and at arrival at Tuborg Havnevej 19 you ask Sophie to come and pay for the taxi (they’ll check departure address and number of persons in the taxi), as well as to order your taxi back.

    If you are by car, you can park for free in front or at the side of Tuborg Havnevej 19. If that is full, there is 3 hours free parking in the parking to the Waterfront shopping mall at the end of the road.

    Public transport by train to Hellerup station, and/or bus (1A, 21, 166), nearest by bus stop is Tuborg Boulevard.

    Where can I contact the organizer with any questions?

    Contact Sophie Labrosse at sfeb@novo.dk

    How do I cancel my participation?

    Please help us respecting our speakers, as well as keeping track of the numbers and optimize lecture and catering to the audience by cancelling as soon as you know that you exceptionally will not be able to make it. You can either cancel through Eventbrite or send an email to Sophie Labrosse (sfeb@novo.dk).

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    Do I have to bring my printed ticket to the event?

    No, you do not have to bring your ticket, but registration is mandatory for participation.