Event by Novo Nordisk Foundation Science Cluster

    Symposium: Genome Editing - from basic principles to applied science

    The aim of this meeting in genome editing is to gather word-leading researchers in the field and experts, both from industry and academia, to raise awareness of the important ongoing applications and explore possible coordinated strategies in the important area of genome manipulation

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    20-21 June 2024

    Background

    Gene editing, i.e., modification of a selected target DNA sequence using precise molecular scissors, has revolutionized the fields of molecular and synthetic biology, biotechnology, and biomedicine. The pivotal discovery that the generation of a Double Strand Break (DSB) at a specific location in the genome of mammalian cell using an endonuclease stimulates DDR, followed by the deletion, insertion, or replacement of DNA sequence at that location, revealed the possibility of targeted gene inactivation and correction of deleterious mutations.

    The use of RNA-guided CRISPR-Cas nucleases (Clustered Regularly Interspaced Short Palindromic Repeats that associate with CRISPR associated proteins) in genome editing has radically altered life sciences, enabling genome modification in living organisms. Gene editing using CRISPR-Cas endonucleases has shown extraordinary potential in a variety of fields, from basic to applied research, and has extended our ability to elucidate the contribution of genetics to disease by promoting the creation of more accurate cellular and animal models of different pathologies.

    Therefore, the relevance of this topic is enormous affecting almost all branches of life sciences from a basic science point of view leading to multiple translational applications in biotechnology and biomedicine.

     

     

     

     

    How to apply?

    Register through the form below. The Scientific Committee will assess all incoming applications and chose participants based on relevance and to obtain a good balance in gender, academic seniority and geographical location. You will receive notice about whether you have received a spot at the conference in the end of April.

    Abstract*

    If you wish to be taken into consideration for a short talk, please include an abstract in your registration.

    Scientific Committee

    • Guillermo Montoya, Novo Nordisk Foundation Center for Protein Research
    • Eric P. Bennett, Novo Nordisk A/S
    • Jan Jakub Zylicz, Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW
    • Mani Arumugam, Novo Nordisk Foundation Center for Basic Metabolic Research
    • Morten Sommer, Novo Nordisk Foundation Center for Biosustainability

    Speakers

    Xu Peng University of Copenhagen, Denmark
    Jan Gorodkin University of Copenhagen, Denmark
    Jakob Nilsson University of Copenhagen, Denmark
    Rasmus Bak Aarhus University, Denmark
    Virginijus Siksnys Vilnius University, Lithuania
    Benedetta Artegiani Utrecht University, Netherlands
    Jacob Corn ETH Zurich, Switzerland
    Anna Cereseto University of Trento, Italy
    Toni Cathomen Freiburg University, Germany
    Angelo Lombardo Vita-Salute San Raffaele University, Italy
    Maria Jasin Memorial Sloan Kettering Cancer Center, America
    Guillermo Montoya University of Copenhagen, Denmark
    Morten Sommer Technical University of Denmark, Denmark