Event by Novo Nordisk Foundation Science Cluster

    Nutrient and Metabolite Sensing

    Nutrients and metabolites are generally considered to function mainly as ‘fuels’ or energy sources. However, key metabolites derived from food components, gut microbiota fermentation and from host intermediary metabolism act as important signaling molecules being sensed by intracellular enzymes, and a large number of selective nuclear and cell surface receptors to control metabolism and other functions throughout the body. These metabolite receptors are highly interesting potential novel drug targets.

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    01-05 November 2015


    Barry Levin New Jersey Medical School, United States
    Bart Staels Université Lille / Institut Pasteur de Lille, France
    Daniel Ketelhuth Karolinska Institutet, Sweden
    Daniele Piomelli University of California, United States
    David Greaves Oxford University, United Kingdom
    Fiona Gribble Cambridge Institute for Medical Reasearch, United Kingdom
    Eric Verdin Gladstone Institute of Virology and Immunology, United States
    David Carling Imperial College, London, United Kingdom
    Grahame Hardie University of Dundee, Scotland
    Jens Nielsen Chalmers University of Technology, Sweden / NNF Center for Biosustainability, Denmark
    Jin Shang Marck Research Laboratories, United States
    Joel Elmquist UT Southwestern Medical Center
    Marc-Emmanuel Dumas Imperial College London, United Kingdom
    Sarkis K. Mazmanian Division of Biology & Biological Engineering, California Institute of Technology, United States
    Stefan Offermanns Max Planck Institute for Heart and Lung Research, Germany
    Tony K.T. Lam Toronto General Research Institute, Canada
    Vincent Poitout Montreal Diabetes Research Center, Université de Montréal, Canada
    Wolfgang Langhans Institute of Food Nutrition and Health, Schwitzerland

    Conference topics

    Conference topics

    GPCR and Nuclear Nutrient Sensors
    Olfactory and Gustatory Mechanisms
    Host-Microbiome Metabolite Interactions
    Enteroendocrine and Afferent Vagal Sensing
    Auto-paracrine sensing in WAT and BAT
    Leukocytes as Metabolite Sensors
    Sensing of Metabolites in the CNS
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