Event by Novo Nordisk Foundation Science Cluster

    Conference: PTMS in Cell Signaling

    Post-translational modifications (PTMs) in cell signaling have evolved as the eukaryotic cell’s most important regulatory mechanism to regulate intracellular protein networks in response to external or internal cues. Site-specific modification of proteins by PTMs such as phosphorylation, ubiquitylation, and acetylation are involved in virtually all signaling pathways that orchestrate fundamental cellular processes including cell cycle progression, apoptosis, the DNA damage response, autophagy, and metabolism. Deregulation of proteins involved in these important cellular responses can often lead to disease, and the enzymes catalyzing addition or removal of PTMs have therefore emerged as promin ttent therapeutic targets. The meeting will focus on the cellular regulation of these fundamental processes by bringing together world leading researchers in the area of PTM functions in different cell signaling networks.

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    12-17 September 2014


    Alfonso Valencia
    Chris Sander
    Eric J. Brown
    Guillermo Montoya
    Hanno Steen
    Henrik Daub
    Jo R. Morris
    John Blenis
    John Diffley
    Karolin Luger
    Marcus Bantscheff
    Margaret Goodell
    Matthias Mann
    Michael Yaffe
    Natalie Ahn
    Pedro Beltrao
    Stephen Elledge
    Tanya Paull
    Tony Hunter
    Yang Shi

    Conference topics

    Conference topics

    Clinical proteomics
    Chromatin biology
    DNA damage signaling
    Cell cycle
    Disease pathways
    Signaling systems and networks
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