Novo Nordisk Foundation Center for Genomic Mechanisms of Disease

The Center facilitates close collaborations between the Broad Institute and Danish researchers investigating the genetics and gene regulation of common complex disease, including type 2 diabetes and obesity.

An initiative that will accelerate efforts to mine genetic data for insights into disease mechanisms—and eventually rationally designed treatments.

International efforts

The Center will align with existing international efforts, sharing data, methodology, and tools to contribute to the roadmap of the International Common Disease Alliance, and working in common cause with investigators from other large-scale efforts such as the Accelerating Medicines Partnership in Common Metabolic Diseases and the Impact of Genomic Variation on Function consortia.

The Center generates systematic datasets that will help researchers around the world understand how human genetic variants affect risk for common complex diseases. All datasets are shared freely with the research community. A key activity of the Center is to launch and facilitate close collaborations between the Broad Institute and researchers at Danish universities, with initial focus on understanding type 2 diabetes and obesity, and mapping human gene regulation.

Research at the Center is carried out at the Broad Institute and at Danish institutions, with exchange of scientists and dedicated training programmes for Danish researchers.